PHNOM PENH: Dementia is a terrible disease for the elderly and children who are responsible for caring for elderly parents. Last year, the US Department of Health and Human Services released a drug that could be used to treat Alzheimer's disease. The team claims that there are 10 types of health problems that can occur many years before the onset of dementia. Does this mean they are finding ways to prevent dementia?

I no longer know my children, I know my grandchildren, I have forgotten everything, I only remember the old story, the past story ... Dementia is a disease discovered by Dr. Alzheimer's psychiatrist and neurologist when treating a patient with memory loss. When the patient died, doctors performed an autopsy on the head and found a brain lesion. That ulcer is one of the main causes of Alzheimer's disease because it interferes with function. The lesion was later named the Amyloïde protein plaque. A protein in the space between the tissues breaks out and gathers into a plaque to attach to a nerve. Wherever it clings, it will damage or kill the nervous system. This is a mechanism that leads to dementia.

And in June 2021, in the United States, the Food and Drug Administration issued a drug license. Aduhelm for the treatment of dementia in the above cases. How effective is the medicine? What should be the hope and trust for patients?

Dr. Antoine Piau, a gynecologist:

"This is a monoclonal antibody drug. Drug molecules bind to proteins that cling to nerves, which in turn cause dementia. Among many other reasons). And this drug will be used on patients who have just fallen into the early stages of dementia. The first step is to help restore the situation. But be careful, this medicine is not to prevent getting sick. In particular, patients can take this medicine as long as they have no other means and means. The second condition of this drug is that the patient must show signs that when taking this drug, the protein plaque decreases or Nerve damage and the last point is a sign that hopefully, more effective drugs can facilitate your daily life. The disease. Does the disease go away after receiving this injection? It is the effect of this drug that doctors have not yet agreed on. That is why it is very important to accept the news of the drug trade with caution. Although this is good news, hopefully, be careful not to be disappointed, because it may There will be changes in the future.”

The treatment of dementia is a hotly debated topic among scientists and researchers.

Signs Before Dementia

What if we find a way to prevent it from getting lost easily?! Prevention is definitely better than cure! There is no cure or interruption of the disease, effective prevention, and treatment of dementia. It is a pillar of the fight against this disease.

A team of researchers identified 10 health problems that appeared several years ago before diagnosing them. Dementia. What kind of health problems can potentially lead to and be associated with dementia many years before the onset of dementia?

Published on March 1, 2022, in The Lancet Digital Health magazine, a large-scale study brings answers. The researchers analyzed the health data of nearly 40,000 French and British patients with dementia and 4 people who do not have dementia. More than 80,000 elderly people have been screened by general practitioners. Each.

Researchers evaluated the onset of dementia in a sample of 123 patients 15 years before dementia symptoms Alzheimer's begins to appear. The analysis identified 10 pre-existing health problems that were most common in dementia patients within 15 years. Acne and dementia for people without dementia.

These include depression, anxiety, stress, deafness, weight loss, dementia Constipation, and chronic fatigue syndrome.

These conditions usually appear between two and 10 years before a patient develops dementia. This is according to the details of the researchers.

Depression and depression were the first two problems associated with dementia for at least nine years before being diagnosed. Alzheimer's disease. Then there is constipation (shingles) and abnormal weight loss.

These results statistically reflect the association between a health problem and the risk of dementia. But this relationship is not scientific proof of health problems and Alzheimer's disease.

Depression or constipation does not always lead to dementia in the future. And this is the first time that constipation has been linked to a potential sign of Alzheimer's disease. It's really amazing! Therefore, more in-depth studies are needed to understand the mechanisms that lead to constipation. Dementia.

Another question that remains to be asked is whether the above health problems are risk factors leading to dementia. The first symptom of dementia?! In either scenario, the researchers predicted their study would continue to analyze data from more than 26 patients. Millions more, as well as expanding studies on other neurological disorders, such as Parkinson's disease.

According to the World Health Organization, Alzheimer's disease is responsible for 60 to 70% of memory loss. By 2030, the planet will have an estimated 82 million people with Alzheimer's disease.